As an adult, Smollett-Bell has starred in the films The Great Debaters (2007) and Temptation: Confessions of a Marriage Counselor (2013). She also had starring roles in a number of TV series, including the NBC sports drama Friday Night Lights (2009–2011), and the HBO vampire drama True Blood (2013–2014). In 2016, Smollett-Bell began playing a leading role as Rosalee, the house slave, in the WGN America period drama Underground. Smollett-Bell has won three NAACP Image Awards. In 2018, Bell was cast as DC Comics superheroine Black Canary in the DC Extended Universe, intended to make her first appearance in Birds of Prey.