In 1996, he landed the role of Romeo Santana on The Steve Harvey Show. In 2001, he played the role of Jermaine in the movie Flossin. In 2002, he appeared in the VH1 TV movie, Play'd: A Hip Hop Story with Toni Braxton. That same year, Santana had a role in the Eddie Murphy comedy Showtime. His last television acting role was on the UPN series, Half & Half; his last film role was a 2003 comedy film, The Blues with Deon Richmond.