Shetty made her acting debut with Baazigar (1993), following which she played a dual role in the action comedy Main Khiladi Tu Anari (1994), both of which were commercial successes. She then featured in several films that fared poorly at the box office and Dhadkan (2000) marked a turning point. She started in dramas Indian (2001), Rishtey (2002), Phir Milenge (2004), Life in a. . . Metro (2007) and Kannada drama Auto Shankar.