He plays the role of Bumper in the musical films Pitch Perfect and Pitch Perfect 2 and Andy in the sitcom Modern Family and Adam Demamp in the sitcom Workaholics. His other roles include Neighbors, The Intern, The Final Girls, Mike and Dave Need Wedding Dates, Game Over, Man! and When We First Met. He has voiced characters in films including Ice Age: Collision Course and The Lego Batman Movie. DeVine has voiced characters on animated series Uncle Grandpa, Penn Zero: Part-Time Hero, and Vampirina.