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Jamil was born in Hampstead, London, England, United Kingdom, to an Indian father and a Pakistani mother. She was born with congenital hearing loss and labyrinthitis, which she has had several operations to correct. She stated in 2015 that she had 70% audibility in her left ear and 50% in her right ear. Jamil says she was "bookish and shy" at school. At the age of nine, she was diagnosed with hypermobile Ehlers-Danlos syndrome, a genetic disorder causing loose joints, joint pain, stretchy skin, and abnormal scar formation. As a teenager, she suffered from anorexia nervosa and did not eat a full meal between the ages of 14 and 17. She has stated that she believes her eating disorder developed due to societal pressure:

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