Glusman was born in The Bronx, New York, where his parents met while studying medicine. The family moved to Oregon when he was six months old to raise him in the Portland area. He is of German Jewish and Irish descent. He attended Lake Oswego High School, and then enrolled at Portland State University, but dropped out after a year. He took acting courses while in college, as well as at the Portland Actors Conservatory. Aspiring to be an actor, he later attended the William Esper Studio in New York.